I’m going to pressure-test this, because there’s a big blind spot in how you’re framing the problem.
First, let’s be clear about what’s happening
What you’re describing is not a liver or antioxidant issue. NAC and glutathione will do almost nothing for the symptoms you’re reporting.
Your core problem is localized and systemic inflammatory response, likely driven by a combination of:
-
Extremely high weekly exposure
700–1400 mg of tren E per week is well beyond what most bodies tolerate, regardless of experience. At that level, inflammation is not a side effect, it’s an expected outcome. -
Carrier oil, concentration, and brew quality
200 mg/ml tren E is notorious for post-injection inflammation, especially from UGLs. Tren is harsh by nature, and at that concentration, tissue irritation is amplified. -
Tren-induced muscle rigidity and CNS stress
The “tightness” that makes squatting miserable is a known tren effect. It’s not just local PIP. Tren increases intracellular tension, calcium dysregulation, and sympathetic nervous system drive. Antioxidants do not fix that.
So no, this isn’t a deficiency problem you can supplement your way out of.
The liver support talk is such a massive distraction here. You’re literally redlining your entire system and wondering why the engine is smoking. At 1.4g of Tren, your body is basically in a state of permanent emergency. No amount of NAC is going to stop your muscle fibers from feeling like frozen rebar when the CNS is being fried this hard. You’re not toxic, you’re just overloaded.
Tren is definitely one of those compounds that gives insane results but doesn’t come without a cost. The inflammatory effects—joint aches, swelling, even acne—can hit hard if you’re not careful. It’s one of those cases where knowing your limits, managing diet, and staying on top of recovery isn’t optional, it’s survival. Definitely not a compound to underestimate.
100% this. people always want a magic supplement to fix tren sides, but at those doses it’s not about deficiencies—it’s just the drug being brutal on your body. PIP, muscle tightness, CNS stress, inflammation—it’s all expected. the only real fixes are lowering dose, spacing injections, or switching compounds. antioxidants aren’t going to touch this.
yep, this is exactly what i ran into. people underestimate how brutal tren really is at high doses—PIP, crazy tightness, and that wired feeling aren’t something you can just supplement away. lowering the dose or spacing pins properly is honestly the only way to make it manageable without wrecking your joints and nervous system.
yep, this is exactly what i ran into. people underestimate how brutal tren really is at high doses—PIP, crazy tightness, and that wired feeling aren’t something you can just supplement away. lowering the dose or spacing pins properly is honestly the only way to make it manageable without wrecking your joints and nervous system.
yep, this makes a ton of sense—tren at those doses is basically guaranteed to jack up inflammation, supplements aren’t gonna fix that
i’ve felt the same post-injection tightness before, and it’s wild how much the carrier oil and concentration matter, definitely not a “just take NAC” situation
honestly, the CNS stress and muscle rigidity are underrated effects—tren literally makes your muscles feel like concrete sometimes
good call pointing out that 700–1400 mg is way past what most people can tolerate, even if you’ve run tren before
sometimes you just gotta respect the compound and adjust doses or injection style instead of chasing a supplement fix
damn, that actually makes a ton of sense — i was wondering why the usual “supplements” advice never seemed to work
700–1400mg is insane, even for experienced guys, no wonder the body’s flipping out
never thought about the carrier oil and concentration being such a big factor, that’s a solid point
tren really does sound like a whole different beast, CNS and muscle rigidity included
